Article

Host-Microbe Multiomic Profiling Reveals Age-Dependent COVID-19 Immunopathology

2024-02-13

Abstract excerpt

Age is a major risk factor for severe coronavirus disease-2019 (COVID-19), yet the mechanisms responsible for this relationship have remained incompletely understood. To address this, we evaluated the impact of aging on host and viral dynamics in a prospective, multicenter cohort of 1,031 patients hospitalized for COVID-19, ranging from 18 to 96 years of age. We performed blood transcriptomics and nasal metatransc...

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Literature Corpus work: 90770425-b02d-56eb-85fd-3bc4f2c37997
DOI: 10.1101/2024.02.11.24301704

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