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Article

A human circulating immune cell landscape in aging and COVID-19

11 Aug 2020

Abstract excerpt

Age-associated changes in immune cells have been linked to an increased risk for infection. However, a global and detailed characterization of the changes that human circulating immune cells undergo with age is lacking. Here, we combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the...

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PMID: 32780218
DOI: 10.1007/s13238-020-00762-2

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