Article

Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients

2021-09-16

Abstract excerpt

Coronavirus Disease 2019 (COVID-19) is especially severe in aged patients, defined as 65 years or older, for reasons that are currently unknown. To investigate the underlying basis for this vulnerability, we performed multimodal data analyses on immunity, inflammation, and COVID-19 incidence and severity as a function of age. Our analysis leveraged age-specific COVID-19 mortality and laboratory testing from a larg...

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Literature Corpus work: ddee4dce-40c1-5f1c-a829-8f601e99f59c
DOI: 10.1101/2021.09.13.21263504

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