Article

DNA interference by a mesophilic Argonaute protein, CbcAgo

2020-01-09

Abstract excerpt

<h4>Background: </h4> : The search for putative enzymes that can facilitate gene editing has recently focused its attention on Argonaute proteins from prokaryotes (pAgos). Though they are structural homologues of human Argonaute protein, which uses RNA guides to interfere with RNA targets, pAgos use ssDNA guides to identify and, in many cases, cut a complementary DNA target. Thermophilic pAgos from Thermus thermo...

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Literature Corpus work: 905d1ce6-e0d0-51ff-98ab-a6e1612766da
DOI: 10.12688/f1000research.18445.2

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