Article

Generation of human alveolar epithelial type I cells from pluripotent stem cells

2023-01-21

Abstract excerpt

In the distal lung, alveolar epithelial type I cells (AT1s) comprise the vast majority of alveolar surface area and are uniquely flattened to allow the diffusion of oxygen into the capillaries. This structure along with a quiescent, terminally differentiated phenotype has made AT1s particularly challenging to isolate or maintain in cell culture. As a result, there is a lack of established models for the study of h...

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Literature Corpus work: 9031207e-7b56-5fa4-9987-33f171a93d0b
DOI: 10.1101/2023.01.19.524655

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