Article

Transcriptomic analysis reveals key pathways influenced by HIV-2 Vpx

2024-01-30

Abstract excerpt

<h4>Background: </h4> Viral protein X (Vpx) is a unique accessory protein encoded by the genome of the Human immunodeficiency virus type 2 (HIV-2) and lineages of the simian immunodeficiency virus of sooty mangabeys. So far, counteracting the cellular restriction factor SAMHD1 and mediating efficient translocation of viral pre-integration complex have been recognized as key functions of Vpx, however, thorough expl...

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Literature Corpus work: 90169c9b-8ca4-5ecd-8c1b-60f19741c289
DOI: 10.21203/rs.3.rs-3894515/v1

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