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Article

A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

2018-11-12

Abstract excerpt

Genetic studies of metabolites have identified thousands of variants many of which are associated with downstream metabolic and obesogenic disorders. However, these studies have relied on univariate analyses, reducing power and limiting context specific understanding. Here we aim to provide an integrated perspective of the genetic basis of metabolites by leveraging the Finnish Metabolic Syndrome In Men (METSIM) co...

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Literature Corpus work
900091bb-1231-5dc8-aff5-598ce3d7da93
DOI
10.1101/461848
Open publication

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A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and contextDOI 10.1101/461848
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