Article

Pleiotropic and sex-specific genetic architecture of circulating metabolic markers

2024-08-01

Abstract excerpt

<h4>Background: </h4> Metabolites in plasma form biosignatures of a range of common complex human diseases. Mapping the genetic architecture and discovering variants with pleiotropic effects across metabolites can reveal underlying mechanisms and potential targets for personalized interventions. <h4>Methods:</h4> We performed univariate and multivariate genome-wide association studies (GWAS) on the Nightingale pan...

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Literature Corpus work: f9dfd351-48f0-5d26-af17-adbf1a509488
DOI: 10.1101/2024.07.30.24311254

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