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Metabolome 2.0: quantitative genetics and network biology of metabolic phenotypes.

Molecular bioSystems - 1 Oct 2012

Dumas Marc-Emmanuel

Abstract excerpt

The characterization of the metabolome has rapidly evolved over two decades, from early developments in analytical chemistry to systems biology. Metabolites and small molecules are not independent; they are organized in biochemical pathways and in a wider metabolic network, which is itself dependent on various genetic and signaling networks for its regulation. Recent advances in genomics, transcriptomics,...

Topics

Chromosome Mapping
Genome-Wide Association Study
Genomics
Humans
Metabolic Networks and Pathways
Metabolome
Metabolomics
Phenotype
Polymorphism, Genetic
Precision Medicine
Quantitative Trait Loci

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Systems Biology

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Identifiers

PMID: 22868675
DOI: 10.1039/c2mb25167a

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