Article

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

2024-08-20

Abstract excerpt

Subcortical brain structures are involved in developmental, psychiatric and neurological disorders. We performed GWAS meta-analyses of intracranial and nine subcortical brain volumes (brainstem, caudate nucleus, putamen, hippocampus, globus pallidus, thalamus, nucleus accumbens, amygdala and, for the first time, the ventral diencephalon) in 74,898 participants of European ancestry. We identified 254 independent lo...

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Literature Corpus work: 23253d2e-408d-5781-8af4-89a514270371
DOI: 10.1101/2024.08.13.24311922

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