Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomere Maintenance Mechanisms Define Clinical Outcome in High-Risk Neuroblastoma

14 Apr 2020

Abstract excerpt

Abstract Neuroblastoma is a childhood cancer with heterogeneous clinical outcomes. To comprehensively assess the impact of telomere maintenance mechanism (TMM) on clinical outcomes in high-risk neuroblastoma, we integrated the C-circle assay [a marker for alternative lengthening of telomeres (ALT)], TERT mRNA expression by RNA-sequencing, whole-genome/exome sequencing, and clinical covariates in 134 neuroblastoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neuroblastoma Research and Treatments
Share to Ocular Oncology and Treatments
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32291317
DOI: 10.1158/0008-5472.can-19-3068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomere Maintenance Mechanisms Define Clinical Outcome in High-Risk NeuroblastomaPMID 32291317Read ↗

Reliable assessment of telomere maintenance mechanisms in neuroblastomaSemantic proximity Read ↗

Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteomeSemantic proximity Read ↗

Reliable assessment of telomere maintenance mechanisms in neuroblastomaSemantic proximity Read ↗

How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?Semantic proximity Read ↗

A mechanistic classification of clinical phenotypes in neuroblastomaSemantic proximity Read ↗

Telomere maintenance is pivotal for high-risk neuroblastomaSemantic proximity Read ↗

Neuroblastoma-Telomere maintenance, deregulated signaling transduction and beyond.Semantic proximity Read ↗

Telomerase Is a Prognostic Marker of Poor Outcome and a Therapeutic Target in NeuroblastomaSemantic proximity Read ↗

Clinical Significance of TERT Promoter Mutations in Neuroblastoma.Semantic proximity Read ↗

Telomere biology including TERT rearrangements in neuroblastoma: a useful indicator for surgical treatments.Semantic proximity Read ↗

Connecting telomere maintenance and regulation to the developmental origin and differentiation states of neuroblastoma tumor cellsSemantic proximity Read ↗

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.