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Article

Telomere biology including TERT rearrangements in neuroblastoma: a useful indicator for surgical treatments.

Journal of pediatric surgery - 1 Dec 2016

Kawashima Masumi, Kojima Masato, Ueda Yuka, Kurihara Sho, Hiyama Eiso

Abstract excerpt

PURPOSE: Our telomere biology study of neuroblastomas (NBLs) has revealed that unfavorable NBLs acquired telomere stabilization by telomerase activation or ALT (alternative lengthening of telomeres). Recently, genomic rearrangements in a region proximal to the telomerase reverse transcriptase (TERT) gene have been discovered in NBLs. In this study, TERT rearrangements were examined in NBLs along with their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27793328
DOI: 10.1016/j.jpedsurg.2016.09.042

Genes

TERT
MYCN
ATRX
DAXX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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