Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?

Biomolecules - 28 Jul 2021

Akter Jesmin, Kamijo Takehiko

Abstract excerpt

Telomere maintenance plays important roles in genome stability and cell proliferation. Tumor cells acquire replicative immortality by activating a telomere-maintenance mechanism (TMM), either telomerase, a reverse transcriptase, or the alternative lengthening of telomeres (ALT) mechanism. Recent advances in the genetic and molecular characterization of TMM revealed that telomerase activation and ALT define...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomic Instability
Share to N-Myc Proto-Oncogene Protein
Share to Neoplasm Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuroblastoma

Share to Telomerase

Share to Telomere

Share to Telomere Homeostasis

Share to X-linked Nuclear Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 34439779
DOI: 10.3390/biom11081112
PMCID: PMC8392161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?PMID 34439779Read ↗

Connecting telomere maintenance and regulation to the developmental origin and differentiation states of neuroblastoma tumor cellsSemantic proximity Read ↗

Telomere biology including TERT rearrangements in neuroblastoma: a useful indicator for surgical treatments.Semantic proximity Read ↗

Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastomaSemantic proximity Read ↗

Telomere maintenance is pivotal for high-risk neuroblastomaSemantic proximity Read ↗

Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteomeSemantic proximity Read ↗

Neuroblastoma-Telomere maintenance, deregulated signaling transduction and beyond.Semantic proximity Read ↗

Telomere Maintenance Mechanisms Define Clinical Outcome in High-Risk NeuroblastomaSemantic proximity Read ↗

Reliable assessment of telomere maintenance mechanisms in neuroblastomaSemantic proximity Read ↗

Reliable assessment of telomere maintenance mechanisms in neuroblastomaSemantic proximity Read ↗

A mechanistic classification of clinical phenotypes in neuroblastomaSemantic proximity Read ↗

Telomerase Is a Prognostic Marker of Poor Outcome and a Therapeutic Target in NeuroblastomaSemantic proximity Read ↗

Clinical features of ATRX or DAXX mutated neuroblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.