Article

Acyloxyacyl Hydrolase Modulates the Gut Microbiome Through Transcriptional Regulators of Corticotropin-Releasing Factor

2021-03-05

Abstract excerpt

<h4>ABSTRACT</h4> Gut microbiome-host interactions play a crucial role in health and disease. Altered gut microbiome composition has been observed in patients with interstitial cystitis/bladder pain syndrome (IC/BPS), a disorder characterized by pelvic pain, voiding dysfunction, and often co-morbid with anxiety/depression. We recently showed that mice deficient for acyloxyacyl hydrolase (AOAH) mimic pelvic pain s...

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Literature Corpus work: 8efe5816-42ca-5890-8a0c-eadedf5ce731
DOI: 10.1101/2021.03.04.433950

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