Article
Acyloxyacyl hydrolase modulates pelvic pain severity.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Mar 2018
Yang Wenbin, Yaggie Ryan E, Jiang Mingchen C, Rudick Charles N, Done Joseph, Heckman Charles J, Rosen John M, Schaeffer Anthony J, Klumpp David J
Abstract excerpt
Chronic pelvic pain causes significant patient morbidity and is a challenge to clinicians. Using a murine neurogenic cystitis model that recapitulates key aspects of interstitial cystitis/bladder pain syndrome (IC), we recently showed that pseudorabies virus (PRV) induces severe pelvic allodynia in BALB/c mice relative to C57BL/6 mice. Here, we report that a quantitative trait locus (QTL) analysis of PRV-induced...
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