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Article

Acyloxyacyl hydrolase is a host determinant of gut microbiome-mediated pelvic pain

28 Jul 2021

Abstract excerpt

Dysbiosis of gut microbiota is associated with many pathologies, yet host factors modulating microbiota remain unclear. Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating condition of chronic pelvic pain often with comorbid urinary dysfunction and anxiety/depression, and recent studies find fecal dysbiosis in patients with IC/BPS. We identified the locus encoding acyloxyacyl hydrolase, Aoah,...

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PMID: 34318715
DOI: 10.1152/ajpregu.00106.2021

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