Article

Stress-activated brain-gut circuits disrupt intestinal barrier integrity and social behaviour

2023-10-27

Abstract excerpt

<title>Abstract</title> <p> Chronic stress underlies the etiology of both major depressive disorder (MDD) and irritable bowel syndrome (IBS), two highly prevalent and debilitating conditions with high rates of co-morbidity. However, it is not fully understood how the brain and gut bi-directionally communicate during stress to impact intestinal homeostasis and stress-relevant behaviours. Using the chronic social...

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Literature Corpus work: 6e37dfbb-72f2-51ae-8b7a-facca4822b6b
DOI: 10.21203/rs.3.rs-3459170/v1

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