Article

APOBEC3B Does Not Promote Tumor Progression in Tp53 Hemizygous Mice

2024-10-01

Abstract excerpt

DNA cytosine deaminase APOBEC3B (A3B) is one of the endogenous sources of somatic mutations in many types of human cancers and is associated with tumor progression rather than tumorigenesis. However, it remains uncertain whether APOBEC3B-induced mutations accelerate tumor progression or not. In this paper, we established a mouse model with A3B overexpression and investigated whether the introduction of A3B overexp...

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Literature Corpus work: 8efbdf87-53af-5925-b9d6-f20946cfa529
DOI: 10.22541/au.172779915.53240920/v1

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