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Linker Histone H1.5 Contributes to Centromere Integrity in Human Cells

2025-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Mammalian H1 linker histones comprise a group of 11 non-allelic variants which have key roles in modulating chromatin. H1 variant specific genomic distribution contributes to fine tuning regulation of gene expression and chromatin architecture. Contradictory reports on the presence and role of H1 histones at centromeres led us to further investigate whether H1s impact centromeric chromatin. In t...

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Literature Corpus work
d2cadb95-af71-5f84-9a79-35245ab2bc62
DOI
10.1101/2025.06.03.657682
Open publication

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Linker Histone H1.5 Contributes to Centromere Integrity in Human CellsDOI 10.1101/2025.06.03.657682
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