Article

A Dynamic population of prophase CENP-C is required for meiotic chromosome segregation

2023-03-13

Abstract excerpt

The centromere is an epigenetic mark that is a loading site for the kinetochore during meiosis and mitosis. This mark is characterized by the H3 variant CENP-A, known as CID in Drosophila . In Drosophila , CENP-C is critical for maintaining CID at the centromeres and directly recruits outer kinetochore proteins after nuclear envelope break down. It is not known, however, if these two functions require the same C...

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Literature Corpus work: 329181e2-51b5-5740-82f3-0ff6400e9882
DOI: 10.1101/2023.03.13.532437

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