Article

G4mer: An RNA language model for transcriptome-wide identification of G-quadruplexes and disease variants from population-scale genetic data

2024-10-03

Abstract excerpt

<h4>ABSTRACT</h4> RNA G-quadruplexes (rG4s) are key regulatory elements in gene expression, yet the effects of genetic variants on rG4 formation remain underexplored. Here, we introduce G4mer, an RNA language model that predicts rG4 formation and evaluates the effects of genetic variants across the transcriptome. G4mer significantly improves accuracy over existing methods, highlighting sequence length and flankin...

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Literature Corpus work: 8e888c2e-3df3-5660-88f5-10651bed3f8a
DOI: 10.1101/2024.10.01.616124

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