Article

Mucosal BCG vaccination reprograms lung interstitial macrophages and enhances antimicrobial defense in mice

2026-02-05

Abstract excerpt

Bacille Calmette–Guérin (BCG) is the only licensed vaccine against tuberculosis (TB) but provides inconsistent protection against disease. Studies in non-human primates show that intravenous BCG confers superior protection compared to intradermal vaccination, yet how different vaccination routes reprogram lung immunity in mice - the primary model for mechanistic studies - remains incompletely defined at single cel...

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Literature Corpus work: bccf0c12-3009-5f3a-8f21-20189c171313
DOI: 10.64898/2026.02.03.703470

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