Article

eQTL mapping in transgenic alpha-synuclein carrying <i>Caenorhabditis elegans</i> recombinant inbred line

2023-08-18

Abstract excerpt

Protein aggregation of α-synuclein (αS) is a genetic and neuropathological hallmark of Parkinson’s disease (PD). Studies in the model nematode Caenorhabditis elegans suggested that variation of αS aggregation depends on the genetic background. However, which genes and genetic modifiers underlie individual differences in αS pathology remains unknown. To study the genotypic-phenotypic relationship of αS aggregation...

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Literature Corpus work: 8e32a527-125c-577b-8cc3-ab5ed6d7b507
DOI: 10.1101/2023.08.18.553811

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