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Article

Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice.

BMC neuroscience - 1 Jan 2001

Specht C G, Schoepfer R

Abstract excerpt

BACKGROUND: The presynaptic protein alpha-synuclein is involved in a range of neurodegenerative diseases. Here we analyze potential compensatory mechanisms in alpha-synuclein null mutant mice. Furthermore, the findings reveal problems that may be associated with inbred mouse strains. RESULTS: Expression profiling by cDNA array technology in a transgenic mouse model revealed striking differences only in the...

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Identifiers

PMID: 11591219
DOI: 10.1186/1471-2202-2-11
PMCID: PMC57740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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