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Enhanced Expression of Human Cyclin G1 (CCNG1) in Tumors, a Novel Biomarker in Development for Cancer Therapy/Gene Therapy

2021-03-08

Abstract excerpt

<h4>Background: </h4> Metastatic cancer is associated with an invariably fatal outcome. However, DeltaRex-G, a tumor- targeted retrovector encoding a CCNG1 inhibitor gene, has induced long term (&gt;10 years) survival of patients with chemo-resistant metastatic pancreatic adenocarcinoma, MPNST, osteosarcoma, B-cell lymphoma, and breast carcinoma. <h4>Objective:</h4> To evaluate the level of CCNG1 expression in tum...

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Literature Corpus work
8e249220-8637-5092-ac00-fb2d5dfb61a6
DOI
10.20944/preprints202103.0213.v1
Open publication

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