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Downregulation of Gankyrin/PSMD10 affects cancer cell growth and proliferation in glioblastoma: <i>in vitro</i> and <i>in vivo</i> study

2024-12-05

Abstract excerpt

The oncoprotein Gankyrin/PSMD10 is upregulated in various cancers, including glioblastoma multiforme (GBM), the most difficult tumor to treat. The heterogeneity of this type of tumor requires a multi-targeted approach to overcome radio- and chemoresistance. Here we aim to investigate the effects of Gankyrin inhibition on glioma cell proliferation and its impact on sensitivity to chemotherapy both in vitro and in...

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Literature Corpus work
058a2d6f-ebd7-5b09-b4e7-cbe6645fae9c
DOI
10.1101/2024.12.02.626412
Open publication

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Downregulation of Gankyrin/PSMD10 affects cancer cell growth and proliferation in glioblastoma: <i>in vitro</i> and <i>in vivo</i> studyDOI 10.1101/2024.12.02.626412
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