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Article

An update on the implications of cyclin D1 in melanomas

9 Mar 2020

Abstract excerpt

Cyclin D1 is a protein encoded by the CCND1 gene, located on 11q13 chromosome, which is a key component of the physiological regulation of the cell cycle. CCND1/cyclin D1 is upregulated in several types of human tumors including melanoma and is currently classified as an oncogene that promotes uncontrolled cell proliferation. Despite the demonstrated importance of CCND1/cyclin D1 as a central oncogene in several...

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PMID: 32147907
DOI: 10.1111/pcmr.12874

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