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Chromosome 1q amplification perturbs a ceRNA network to promote melanoma metastasis

2021-11-14

Abstract excerpt

<h4>SUMMARY</h4> Somatic copy number alterations (CNAs) promote cancer, but the underlying driver genes are often not obvious when only the functions of the encoded proteins are considered. mRNAs can act as competitive endogenous miRNA sponges (ceRNAs) to post-transcriptionally regulate gene expression in a protein coding-independent manner. However, whether ceRNAs contribute to the oncogenic effects of CNAs is u...

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Literature Corpus work
367ee3b3-821e-5943-b429-4673683996a0
DOI
10.1101/2021.11.14.468531
Open publication

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Chromosome 1q amplification perturbs a ceRNA network to promote melanoma metastasisDOI 10.1101/2021.11.14.468531
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