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Composite CYP3A (CYP3A4 and CYP3A5) phenotypes and influences on tacrolimus dose adjusted concentration in adult heart transplant recipients

2023-05-16

Abstract excerpt

<title>Abstract</title> <p><italic>CYP3A5</italic> genetic variants are associated with tacrolimus metabolism. Controversy remains on whether <italic>CYP3A4</italic> increased [*<italic>1B</italic> (rs2740574), *<italic>1G</italic> (rs2242480)] and decreased function [*22 (rs35599367)] genetic variants provide additional information. This study aims to address whether tacrolimus dose-adjusted trough concentration...

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Literature Corpus work
8e0dd8ff-ff80-5bc1-b91d-30e13c6aa992
DOI
10.21203/rs.3.rs-2921796/v1
Open publication

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Composite CYP3A (CYP3A4 and CYP3A5) phenotypes and influences on tacrolimus dose adjusted concentration in adult heart transplant recipientsDOI 10.21203/rs.3.rs-2921796/v1
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