Article

PROS1 released by human lung basal cells upon SARS-CoV-2 infection facilitates epithelial cell repair and limits inflammation

2024-09-13

Abstract excerpt

Factors governing the coagulopathy and pneumonitis associated with severe viral infections remain unresolved. We previously found that the expression of protein S (PROS1) is increased in lung epithelium of patients with mild COVID-19 as compared to severe COVID-19. We hypothesised that PROS1 may exert a local effect that protects the upper airway against severe inflammation by modulating epithelial and myeloid cel...

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Identifiers and source

Literature Corpus work: 8dd6fa00-d8aa-5490-ade8-76b88bc79b9c
DOI: 10.1101/2024.09.11.612489

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