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Surfactant deficiency increases SARS-CoV-2 canonical and non-canonical viral entry to lung epithelial cells and exacerbates intrapulmonary inflammatory responses

2023-04-18

Abstract excerpt

<title>Abstract</title> <p>The prevalence of “Long COVID”, including among vaccinated patients, is just one of the conundrums that indicate how much remains unknown about the lung’s response to viral infection, particularly to SARS-CoV-2 for which the lung is the point of entry. Therefore, we used an <italic>in vitro</italic> human lung system to enable a prospective, unbiased, sequential single cell level analys...

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Literature Corpus work
e1b243f4-9898-5708-bacf-1f4bd55a839c
DOI
10.21203/rs.3.rs-2694520/v1
Open publication

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Surfactant deficiency increases SARS-CoV-2 canonical and non-canonical viral entry to lung epithelial cells and exacerbates intrapulmonary inflammatory responsesDOI 10.21203/rs.3.rs-2694520/v1
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