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SARS-CoV-2 activates lung epithelia cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients by single-cell sequencing

2020-05-13

Abstract excerpt

<h4>Objective</h4> The outbreak of Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has become a global health emergency. We aim to decipher SARS-CoV-2 infected cell types, the consequent host immune response and their interplay in the lung of COVID-19 patients. <h4>Design</h4> We analyzed single-cell RNA sequencing (scRNA-seq) data of lung samples from 17 subjects (6 severe COVID-19 patients, 3...

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Literature Corpus work
0e08b8c7-ff77-523b-a52b-186da7e0cf90
DOI
10.1101/2020.05.08.20096024
Open publication

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SARS-CoV-2 activates lung epithelia cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients by single-cell sequencingDOI 10.1101/2020.05.08.20096024
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