Article

A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV2 at the immune-epithelial interface

2021-09-29

Abstract excerpt

<h4>ABSTRACT</h4> Infection by SARS-CoV2 provokes a potentially fatal pneumonia with multiorgan failure, and high systemic inflammation. To gain mechanistic insight and ferret out the root of this immune dysregulation, we modeled by in vitro co-culture the interactions between infected epithelial cells and immunocytes. A strong response was induced in monocytes and B cells, with a SARS-CoV2-specific inflammatory...

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Literature Corpus work: e2177497-de5c-5e5b-a1a8-983e5e13c516
DOI: 10.1101/2021.09.29.462202

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