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Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion

2022-09-07

Abstract excerpt

<h4>Background: </h4> Quantitative proteomics is able to provide a comprehensive, unbiased description of changes to cells caused by viral infection, but interpretation may be complicated by differential changes in infected and uninfected ‘bystander’ cells, or the use of non-physiological cellular models. <h4>Methods: </h4>: In this paper, we use fluorescence-activated cell sorting (FACS) and quantitative proteom...

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Literature Corpus work
d8375fb8-76e2-514c-9766-2441b9bb974f
DOI
10.12688/wellcomeopenres.17946.1
Open publication

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Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasionDOI 10.12688/wellcomeopenres.17946.1
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