Article

In vivo and in vitro validation of GATA-3 suppression for correcting impaired adipogenesis, restoring insulin sensitivity, and lowering risk of T2D

2022-06-07

Abstract excerpt

<title>Abstract</title> <p>Purpose Impaired adipogenesis is associated with development of insulin resistance and increased risk of type 2 diabetes (T2D). GATA Binding Protein 3 (GATA3) is implicated in impaired adipogenesis and the onset of insulin resistance. Therefore, we hypothesize that inhibition of GATA3 could promote adipogenesis, restore healthy fat distribution, and enhance insulin signaling. Methods...

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Literature Corpus work: 8db84d25-1055-5411-9daf-b57785a434c7
DOI: 10.21203/rs.3.rs-1646980/v1

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