Back to search

Article

Adipose stromal cells increase insulin sensitivity and decrease liver gluconeogenesis in a mouse model of type 1 diabetes mellitus

2024-04-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Diabetic ketoacidosis (DKA) is a serious complication of hyperglycemic emergency caused by insulin deficiency through accelerated liver gluconeogenesis and glycogenolysis. DKA is most common in type 1 diabetes (T1D). Transplantation of islet cells and pancreas is an alternative to insulin injection for treating T1D. However, this alternative is only suitable for...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3dc4fa23-89be-5944-8e18-4f726d50325b
DOI
10.21203/rs.3.rs-4198474/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Adipose stromal cells increase insulin sensitivity and decrease liver gluconeogenesis in a mouse model of type 1 diabetes mellitusDOI 10.21203/rs.3.rs-4198474/v1
Immune cell–adipose tissue crosstalk in metabolic diseases with a focus on type 1 diabetesSemantic proximity
The single-cell RNA sequencing (scRNA-seq) transcriptome profile of pancreatic islets in three types of diabetic mice and its pathological changesSemantic proximity
Harnessing distinct tissue-resident immune niches <i>via</i> S100A9/TLR4 improves ketone, lipid, and glucose metabolismSemantic proximity
Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and anti-inflammatory effects in type 2 diabetic ratsSemantic proximity
Stem cells as a therapeutic target for diabetesSemantic proximity
iPSC-derived exosomes promote diabetic wound healing by attenuating inflammatory responsesSemantic proximity
Secretome analysis of human and rat pancreatic islets co-cultured with adipose-derived stromal cells reveals a signature with enhanced regenerative capacitiesSemantic proximity
Uncovering the link between diabetes and cardiovascular diseases: insights from adipose-derived stem cells.Semantic proximity
Overexpression of IL-10 in Adipose Mesenchymal Stem Cells Promotes Wound Healing in Diabetic MiceSemantic proximity
The Transcriptomic Evidence on the Role of Abdominal Visceral vs. Subcutaneous Adipose Tissue in the Pathophysiology of Diabetes in Asian Indians Indicates the Involvement of BothSemantic proximity
MyD88 Inhibition Ameliorates Diabetes-Induced Hepatic Inflammation and Gluconeogenesis Through Adipose IL-10 InductionSemantic proximity
Alpha-1 Antitrypsin Overexpressing Mesenchymal Stem/Stromal Cells Reverses Type 1 Diabetes via Promoting Treg Function and CD8 <sup>+</sup> T cell exhaustionSemantic proximity
Select a neighboring publication to make it the new centre.