Article

CLPX regulates mitochondrial fatty acid β-oxidation by modulating protein complex formation in liver cells

2022-04-26

Abstract excerpt

<title>Abstract</title> <p>Mitochondrial fatty acid oxidation (β-oxidation) is an essential metabolic process for energy production in eukaryotic cells, but the regulatory mechanisms of this pathway are largely unknown. In the present study, we found that several enzymes involved in β-oxidation are associated with CLPX, the AAA + unfoldase that is a component of the mitochondrial matrix protease ClpXP. Deletion o...

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Literature Corpus work: 8ce8df2a-c951-55ca-b111-505b6bb94f8a
DOI: 10.21203/rs.3.rs-1388288/v1

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