Article
Studies on the regulation of the mitochondrial alpha-ketoacid dehydrogenase complexes and their kinases.
Advances in enzyme regulation - 1 Jan 1997
Harris R A, Hawes J W, Popov K M, Zhao Y, Shimomura Y, Sato J, Jaskiewicz J, Hurley T D
Abstract excerpt
Five mitochondrial protein kinases, all members of a new family of protein kinases, have now been identified, cloned, expressed as recombinant proteins, and partially characterized with respect to catalytic and regulatory properties. Four members of this unique family of eukaryotic protein kinases correspond to pyruvate dehydrogenase kinase isozymes which regulate the activity of the pyruvate dehydrogenase...
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