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Article

Peroxisomal Pex11 is a pore-forming protein homologous to TRPM channels.

Biochimica et biophysica acta - 1 Feb 2016

Mindthoff Sabrina, Grunau Silke, Steinfort Laura L, Girzalsky Wolfgang, Hiltunen J Kalervo, Erdmann Ralf, Antonenkov Vasily D

Abstract excerpt

More than 30 proteins (Pex proteins) are known to participate in the biogenesis of peroxisomes-ubiquitous oxidative organelles involved in lipid and ROS metabolism. The Pex11 family of homologous proteins is responsible for division and proliferation of peroxisomes. We show that yeast Pex11 is a pore-forming protein sharing sequence similarity with TRPM cation-selective channels. The Pex11 channel with a...

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Identifiers

PMID: 26597702
DOI: 10.1016/j.bbamcr.2015.11.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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