Article

Disrupted basal ganglia output during movement preparation in hemi-parkinsonian mice accounts for behavioral deficits

2020-06-20

Abstract excerpt

Parkinsonian motor deficits are associated with elevated inhibitory output from the basal ganglia (BG). However, several features of Parkinson’s disease (PD) have not been accounted for by this simple “rate model” framework, including the observation in PD patients that movements guided by external stimuli are less impaired than otherwise-identical movements generated based on internal goals. Is this difference in...

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Identifiers and source

Literature Corpus work: 8cd94b96-db02-5ff9-981e-612a79098188
DOI: 10.1101/2020.06.19.160457

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