Article

Determining rewiring effects of alternatively spliced isoforms on protein-protein interactions using a computational approach

2018-01-30

Abstract excerpt

The critical role of alternative splicing (AS) in cell functioning has recently become apparent, whether in studying tissue-or cell-specific regulation, or understanding molecular mechanisms governing a complex disorder. Studying the rewiring, or edgetic, effects of alternatively spliced isoforms on protein interactome can provide system-wide insights into these questions. Unfortunately, high-throughput experiment...

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Literature Corpus work: 8c8c18cc-77da-5b18-bb90-9cf2c4d3ffa7
DOI: 10.1101/256834

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