Article

Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases

2021-07-14

Abstract excerpt

Alternative splicing (AS) is an important aspect of gene regulation. Nevertheless, its role in molecular processes and pathobiology is far from understood. A roadblock is that tools for the functional analysis of AS-set events are lacking. To mitigate this, we developed NEASE, a tool integrating pathways with protein-protein and domain-domain interactions to functionally characterize AS events. We show in four app...

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Literature Corpus work: 9c4827b9-ee6e-5361-a42b-48316105e7de
DOI: 10.1101/2021.07.14.452376

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