Article

CanIsoNet: A Database to Study the Functional Impact of Isoform Switching Events in Diseases

2021-09-18

Abstract excerpt

<h4>Motivation</h4> Alternative splicing, as an essential regulatory mechanism in normal mammalian cells, is frequently disturbed in cancer and other diseases. Switches in the expression of most dominant alternative isoforms can alter protein interaction networks of associated genes giving rise to a disease or disease progression. Here, we present CanIsoNet (disease-specific isoform interaction network), a databa...

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Literature Corpus work: ba2c3fa9-8185-5c3c-a137-82068de65e38
DOI: 10.1101/2021.09.17.460795

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