Article
Linear motifs confer functional diversity onto splice variants.
Nucleic acids research - 1 Aug 2012
Weatheritt Robert J, Davey Norman E, Gibson Toby J
Abstract excerpt
The pre-translational modification of messenger ribonucleic acids (mRNAs) by alternative promoter usage and alternative splicing is an important source of pleiotropy. Despite intensive efforts, our understanding of the functional implications of this dynamically created diversity is still incomplete. Using the available knowledge of interaction modules, particularly within intrinsically disordered regions (IDRs),...
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