Article

Systematic evaluation of isoform function in literature reports of alternative splicing

2018-04-17

Abstract excerpt

<h4>ABSTRACT</h4> Although most mammalian genes have multiple isoforms, an ongoing debate is whether these isoforms are all functional as well as the extent to which they increase the genome’s functional repertoire. To ground this debate in data, we established a curation framework for evaluating experimental evidence of functionally distinct splice isoforms (FDSIs) and analyzed splice isoform function for over 7...

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Literature Corpus work: c3a96e38-d055-5356-9975-1cf8b85909e7
DOI: 10.1101/303412

Open publication

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