Article
EccDNA-oriented HGF potential role in platinum resistance and cancer progression based on differential abundance analysis of eccDNAs in lung cancer
2026-03-13
Abstract excerpt
<title>Abstract</title> <p>Extrachromosomal circular DNAs (eccDNAs) play a role in tumorigenesis and tumor progression. This study aims to identify eccDNA biomarkers associated with platinum-based chemoresistance and to elucidate their underlying molecular mechanisms. Plasma samples were collected from four patients who did not respond to platinum-based chemotherapy and nine who did respond. We conducted eccDNA c...
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Identifiers and source
- Literature Corpus work
- 8c79519c-d598-5652-9415-78841d41dc7f
- DOI
- 10.21203/rs.3.rs-8973876/v1