Article

Mechanical Memory Primes Cells for Confined Migration

2025-09-08

Abstract excerpt

<h4>Summary</h4> When migratory cells move from one stiffness niche to another in vivo , they are exposed to highly confined spaces imposed by dense extracellular matrix (ECM) networks and inter-tissue boundaries. Cells that originate from one niche possess distinct mechanosensitive adaptations that influence their response to their new niche, a concept known as mechanical memory. However, the mechanisms by whic...

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Literature Corpus work: 8c76f7c9-0589-5a51-89d5-b2d2b100191c
DOI: 10.1101/2025.09.07.674701

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