Article

Persistent confined migration confers permanent nuclear and functional changes in migrating cells

2023-01-07

Abstract excerpt

Nuclear deformability plays a critical role in cell migration. During this process, the remodeling of internal components of the nucleus has a direct impact on DNA damage and cell behavior; however, how persistent migration promotes nuclear changes leading to phenotypical and functional consequences remains poorly understood. Here, we described that the persistent migration through physical barriers was sufficient...

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Identifiers and source

Literature Corpus work: 608b1073-7b57-5069-9927-cf06ccbb8839
DOI: 10.1101/2023.01.05.522838

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