Article

Trex-QTL: A mixture-model for identification of genetic effects with global effects on molecular phenotypes

2026-08-13

Abstract excerpt

Genetic variants that are associated with changes in gene expression, termed eQTLs, are major drivers of complex traits and human disease. While thousands of cis expression quantitative trait loci (cis-eQTLs) have been reliably identified, detecting trans-eQTL effects has proven to be challenging due to insufficient statistical power, lack of comparable tissues and cohorts, and low reproducibility across studies....

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Literature Corpus work: 8c6e9b20-220b-5551-9b2d-ff624331e0e1
DOI: 10.64898/2026.08.07.743622

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