Article

PATJ regulates cell stress responses and vascular remodeling post-stroke

2024-07-22

Abstract excerpt

PALS1-associated tight junction (PATJ) protein is linked to metabolic disease and stroke in human genetic studies. Despite the recognized role of PATJ in cell polarization, its specific functions in metabolic disease and ischemic stroke recovery remain largely unexplored. Using a mouse model of stroke, we found post-ischemic stroke duration-dependent increase of PATJ abundance in endothelial cells. PATJ knock-out...

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Literature Corpus work: 8c383560-591b-5f1a-a6f4-5a44ca08d86e
DOI: 10.1101/2024.07.17.603777

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